HitPredict

Interactor 1: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Interactor 2: MTMR6 (Q9Y217)
Myotubularin-related protein 6 (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64)
Gene: MTMR6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.60	0.541

Property	Details
Experiments	28065597
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1374 Hs			1 621
+	Hs
		1168399 LMTK1_HUMAN (1-1374): 0: 976: 100.00		MTMR8_HUMAN (1-564): 0: 765: 59.23
+	Hs
		1168406 LMTK1_HUMAN (1-1374): 0: 976: 100.00		MTMR9_HUMAN (2-547): 0: 664: 33.94
+	Hs
		1219453 LMTK2_HUMAN (9-1366): 0: 690: 29.74		MTMR6_HUMAN (1-621): 0: 904: 100.00
+	Hs
		1168424 LMTK1_HUMAN (1-1374): 0: 976: 100.00		MTMRA_HUMAN (35-546): 2.22e-141: 431: 22.74
+	Hs
		601617 FGFR2_HUMAN (17-456): 6.43e-126: 412: 19.75		MTMR6_HUMAN (1-621): 0: 904: 100.00
+	Hs
		508272 FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00		MTMR6_HUMAN (1-621): 0: 904: 100.00
+	Hs
		309494 LMTK1_HUMAN (1-1374): 0: 976: 100.00		MTMR5_HUMAN (129-233): 1.49e-23: 108: 23.31
+	Hs
		601573 FGFR2_HUMAN (17-456): 6.43e-126: 412: 19.75		MTMR9_HUMAN (2-547): 0: 664: 33.94
+	Hs
		433752 LYN_HUMAN (109-410): 9.62e-106: 347: 24.75		MTMR1_HUMAN (2-541): 0: 719: 35.94
+	Hs
		1031181 PTK7_HUMAN (32-391): 2.34e-37: 155: 31.90		MTMR6_HUMAN (1-621): 0: 904: 100.00
+	Hs
		601507 FGFR2_HUMAN (17-456): 6.43e-126: 412: 19.75		MTMR3_HUMAN (29-516): 0: 548: 32.97
+	Hs
		1031131 PTK7_HUMAN (32-391): 2.34e-37: 155: 31.90		MTMR1_HUMAN (2-541): 0: 719: 35.94
+	Hs
		1031162 PTK7_HUMAN (32-391): 2.34e-37: 155: 31.90		MTMR9_HUMAN (2-547): 0: 664: 33.94
+	Hs
		59909 EPHA3_HUMAN (12-404): 1.11e-104: 358: 23.74		MTMRB_HUMAN (22-489): 4.2e-107: 340: 20.84
+	Hs
		1031174 PTK7_HUMAN (32-391): 2.34e-37: 155: 31.90		MTMRA_HUMAN (35-546): 2.22e-141: 431: 22.74
+	Hs
		309433 FGFR1_HUMAN (28-460): 6.26e-120: 396: 21.00		MTMR5_HUMAN (129-233): 1.49e-23: 108: 23.31
+	Hs
		309426 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		MTMR5_HUMAN (129-233): 1.49e-23: 108: 23.31
+	Hs
		385110 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		MTMRD_HUMAN (129-234): 5.21e-19: 94: 17.65