HitPredict

Interactor 1: LMTK1 (Q6ZMQ8)
Serine/threonine-protein kinase LMTK1 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase) (AATYK) (Brain apoptosis-associated tyrosine kinase) (CDK5-binding protein) (Lemur tyrosine kinase 1) (p35-binding protein) (p35BP)
Gene: AATK

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1374 Hs			1 605
+	Hs
		1168437 LMTK1_HUMAN (1-1374): 0: 976: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		793002 LMTK1_HUMAN (1-1374): 0: 976: 100.00		LIS1_HUMAN (174-494): 8.99e-74: 243: 21.37
+	Hs
		609202 FGFR3_HUMAN (29-448): 5.82e-123: 403: 23.42		LIS1_HUMAN (174-494): 8.99e-74: 243: 21.37
+	Hs
		196942 LYN_HUMAN (109-410): 9.62e-106: 347: 24.75		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Hs
		384438 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		LIS1_HUMAN (174-494): 8.99e-74: 243: 21.37
+	Hs
		209376 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Hs
		384596 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		196939 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Hs
		385480 NTRK1_HUMAN (120-398): 5.02e-34: 143: 32.77		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67