Interactor 1: SYNE3 (Q6ZMZ3)
Nesprin-3 (KASH domain-containing protein 3) (KASH3) (Nuclear envelope spectrin repeat protein 3)
Gene: SYNE3

Interactor 2: SUN2 (Q9UH99)
SUN domain-containing protein 2 (Protein unc-84 homolog B) (Rab5-interacting protein) (Rab5IP) (Sad1/unc-84 protein-like 2)
Gene: SUN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 34079125, 33058875
Identification Methods proximity labelling technology, x-ray crystallography, molecular sieving
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains KASH~Sad1_UNC
Common GO terms GO:0005635 - nuclear envelope
GO:0007097 - nuclear migration
GO:0031965 - nuclear membrane
GO:0034993 - meiotic nuclear membrane microtubule tethering complex
GO:0140444 - cytoskeleton-nuclear membrane anchor activity
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 975
Hs

1 717
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Last updated: 15 Jul 2024