HitPredict

Interactor 1: AEBP2 (Q6ZN18)
Zinc finger protein AEBP2 (Adipocyte enhancer-binding protein 2) (AE-binding protein 2)
Gene: AEBP2

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26091241, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 517 Hs			1 605
+	Hs
		1168999 AEBP2_HUMAN (1-517): 1.14e-154: 453: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		485153 GLI3_HUMAN (209-388): 1.72e-49: 185: 24.32		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		436762 GLI1_HUMAN (231-388): 5.87e-49: 183: 30.91		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		485097 GLI2_HUMAN (260-388): 2.03e-48: 182: 27.91		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Mm
		1012688 GLI2_MOUSE (260-388): 9.32e-49: 183: 27.91		FBW1A_MOUSE (1-605): 0: 547: 98.68
+	Hs
		485149 GLI3_HUMAN (209-388): 1.72e-49: 185: 24.32		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		485094 GLI2_HUMAN (260-388): 2.03e-48: 182: 27.91		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		313663 ZIC2_HUMAN (267-395): 5.25e-31: 127: 24.81		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Mm
		1225109 GLIS1_MOUSE (263-395): 2.66e-46: 174: 28.57		FBXW7_MOUSE (76-527): 2.98e-83: 277: 23.71
+	Hs
		632844 TYY1_HUMAN (263-385): 1.34e-19: 92.9: 21.95		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		209379 GLI1_HUMAN (231-388): 5.87e-49: 183: 30.91		PLRG1_HUMAN (417-604): 2.83e-38: 150: 23.47
+	Dm
		585792 CI_DROME (259-388): 2.33e-50: 188: 28.46		Q9VDE3_DROME (466-605): 2.66e-30: 126: 29.37
+	Hs
		632676 TYY1_HUMAN (263-385): 1.34e-19: 92.9: 21.95		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33