HitPredict

Interactor 1: KDM1A (Q6ZQ88)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2)
Gene: KDM1A

Interactor 2: TREF1 (Q8BXJ2)
Transcriptional-regulating factor 1 (Transcriptional-regulating protein 132) (Zinc finger transcription factor TReP-132)
Gene: Trerf1

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709266
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003714 - transcription corepressor activity GO:0006357 - regulation of transcription by RNA polymerase II GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 853 Mm			1 1205
+	Hs
		232471 KDM1A_HUMAN (1-853): 0: 1019: 98.12		MTA3_HUMAN (715-1076): 6.23e-60: 218: 14.29
+	Hs
		232141 KDM1A_HUMAN (1-853): 0: 1019: 98.12		MTA1_HUMAN (715-1086): 1.28e-56: 212: 16.09
+	Hs
		232578 KDM1A_HUMAN (1-853): 0: 1019: 98.12		RCOR1_HUMAN (784-1132): 7.52e-58: 210: 16.58
+	Hs
		232311 KDM1A_HUMAN (1-853): 0: 1019: 98.12		RCOR2_HUMAN (744-1088): 5.01e-54: 199: 18.44
+	Hs
		232559 KDM1A_HUMAN (1-853): 0: 1019: 98.12		CHD7_HUMAN (184-657): 1.62e-50: 198: 16.67
+	Mm
		1169771 KDM1A_MOUSE (1-853): 0: 998: 100.00		MTA3_MOUSE (715-1076): 3.28e-59: 217: 13.90
+	Mm
		1169746 KDM1A_MOUSE (1-853): 0: 998: 100.00		RCOR1_MOUSE (784-1132): 2.51e-57: 208: 16.85
+	Hs
		231926 KDM1A_HUMAN (1-853): 0: 1019: 98.12		MTA2_HUMAN (707-1122): 7.07e-48: 184: 14.06
+	Hs
		232560 KDM1A_HUMAN (1-853): 0: 1019: 98.12		RCOR3_HUMAN (787-1157): 1.25e-48: 183: 17.82
+	Mm
		1169742 KDM1A_MOUSE (1-853): 0: 998: 100.00		RCOR2_MOUSE (744-1088): 8.5e-55: 202: 18.16
+	Mm
		1161359 KDM1A_MOUSE (1-853): 0: 998: 100.00		RCOR3_MOUSE (741-1077): 2.04e-52: 193: 17.90
+	Mm
		1169714 KDM1A_MOUSE (1-853): 0: 998: 100.00		RERE_MOUSE (781-989): 3.76e-12: 73.4: 18.47
+	Dm
		1123846 LSDA_DROME (36-845): 0: 836: 50.82		RCOR_DROME (716-1147): 2.08e-42: 166: 16.89
+	Ce
		1090390 KDM1A_CAEEL (183-832): 9.97e-178: 533: 27.60		RCORB_CAEEL (683-1125): 1.85e-46: 178: 13.35
+	Ce
		1280107 KDM1A_CAEEL (183-832): 9.97e-178: 533: 27.60		RCORA_CAEEL (781-959): 6.48e-16: 84.6: 18.23
+	Hs
		1056891 KDM1B_HUMAN (124-496): 1.43e-82: 284: 23.53		MDC1_HUMAN (168-1111): 3.44e-45: 181: 12.32