Interactor 1: KDM1A (Q6ZQ88)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2)
Gene: KDM1A

Interactor 2: RCOR1 (Q8CFE3)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 26206133, 34709266, 17392792, 22297846
Identification Methods affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Amino_oxidase~Myb_DNA-binding
Common GO terms GO:0003682 - chromatin binding
GO:0003714 - transcription corepressor activity
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0019899 - enzyme binding
GO:0045654 - positive regulation of megakaryocyte differentiation
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 853
Mm

1 480
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
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+ Hs
+ Mm
+ Mm
+ Mm
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+ Dm
+ Ce
+ Ce

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Last updated: 15 Jul 2024