Interactor 1: SRCAP (Q6ZRS2)
Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator)
Gene: SRCAP

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.925

The method score is based on:

Property Details
Experiments 28514442, 28561026, 33961781, 35271311, 16230350
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~TIP49, SNF2-rel_dom~TIP49
Common GO terms GO:0000786 - nucleosome
GO:0000812 - Swr1 complex
GO:0003713 - transcription coactivator activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 5 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 3230
Hs

1 456
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Last updated: 15 Jul 2024