HitPredict

Interactor 1: SGK1 (O00141)
Serine/threonine-protein kinase Sgk1 (EC 2.7.11.1) (Serum/glucocorticoid-regulated kinase 1)
Gene: SGK1

Interactor 2: RICTR (Q6R327)
Rapamycin-insensitive companion of mTOR (AVO3 homolog) (hAVO3)
Gene: RICTOR

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.629

Property	Details
Experiments	20832730, 18925875
Identification Methods	enzymatic study, affinity chromatography technology, protein kinase assay
Interaction Type	direct interaction, physical association, phosphorylation reaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 1708
+	Hs
		681904 AKT1_HUMAN (25-426): 4.84e-154: 446: 41.57		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		408632 KPCB_HUMAN (27-430): 4.08e-146: 433: 37.53		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		983861 KPCZ_HUMAN (6-426): 2.47e-146: 430: 36.51		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		566418 KPCA_HUMAN (27-430): 1.24e-144: 429: 37.32		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Hs
		616715 KS6B1_HUMAN (91-429): 1.64e-145: 426: 45.35		RICTR_HUMAN (1-1708): 0: 2775: 100.00
+	Sc
		520613 YPK1_YEAST (83-423): 1.04e-103: 323: 50.73		TSC11_YEAST (61-991): 0: 911: 24.48
+	Sc
		579940 YPK2_YEAST (83-423): 8.39e-102: 318: 50.15		TSC11_YEAST (61-991): 0: 911: 24.48