HitPredict

Interactor 1: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Interactor 2: M4K3 (Q8IVH8)
Mitogen-activated protein kinase kinase kinase kinase 3 (EC 2.7.11.1) (Germinal center kinase-related protein kinase) (GLK) (MAPK/ERK kinase kinase kinase 3) (MEK kinase kinase 3) (MEKKK 3)
Gene: MAP4K3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 783 Hs			1 894
+	Hs
		1172422 TRI67_HUMAN (1-783): 0: 593: 100.00		M4K5_HUMAN (1-894): 0: 940: 65.41
+	Hs
		647914 TRI67_HUMAN (1-783): 0: 593: 100.00		MARK3_HUMAN (9-622): 2.54e-141: 439: 16.67
+	Hs
		1170538 TRI67_HUMAN (1-783): 0: 593: 100.00		MARK2_HUMAN (2-603): 2.82e-134: 422: 17.02
+	Hs
		681909 TRI67_HUMAN (1-783): 0: 593: 100.00		AKT1_HUMAN (6-341): 6.7e-134: 410: 23.70
+	Hs
		682189 TRI67_HUMAN (1-783): 0: 593: 100.00		AKT2_HUMAN (5-344): 8.04e-134: 410: 22.92
+	Hs
		616716 TRI67_HUMAN (1-783): 0: 593: 100.00		KS6B1_HUMAN (8-440): 7.76e-129: 399: 21.57
+	Hs
		1023065 TRI67_HUMAN (1-783): 0: 593: 100.00		STK4_HUMAN (10-288): 2.22e-119: 373: 46.43
+	Hs
		1027387 TRI67_HUMAN (1-783): 0: 593: 100.00		STK3_HUMAN (10-288): 2.29e-117: 368: 45.36
+	Hs
		1172483 TRI67_HUMAN (1-783): 0: 593: 100.00		STK24_HUMAN (9-291): 7.65e-116: 362: 46.67
+	Hs
		1071653 TRI67_HUMAN (1-783): 0: 593: 100.00		KS6A2_HUMAN (14-326): 2.08e-97: 323: 23.44
+	Hs
		1172202 TRI67_HUMAN (1-783): 0: 593: 100.00		TNIK_HUMAN (6-290): 6.53e-73: 264: 48.32
+	Hs
		324829 TRI67_HUMAN (1-783): 0: 593: 100.00		M4K4_HUMAN (8-290): 6.77e-67: 245: 47.28
+	Hs
		1183133 TRI36_HUMAN (115-771): 5.52e-100: 327: 20.16		MARK2_HUMAN (2-603): 2.82e-134: 422: 17.02
+	Mm
		949339 TRI46_MOUSE (1-769): 7.66e-98: 322: 20.36		TNIK_MOUSE (6-290): 5.69e-73: 264: 48.32
+	Hs
		1318737 TRIM2_HUMAN (194-767): 1.51e-82: 280: 15.95		TNIK_HUMAN (6-290): 6.53e-73: 264: 48.32
+	Mm
		949424 TRIM3_MOUSE (190-767): 6.68e-78: 268: 14.85		TNIK_MOUSE (6-290): 5.69e-73: 264: 48.32
+	Hs
		537109 TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77		STK26_HUMAN (3-291): 7.94e-118: 366: 46.05
+	Hs
		131546 TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77		STK25_HUMAN (8-372): 1.06e-116: 364: 40.46
+	Hs
		1071675 TRI11_HUMAN (1-121): 1.6e-09: 63.2: 20.66		KS6A2_HUMAN (14-326): 2.08e-97: 323: 23.44
+	Hs
		537127 TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77		TNIK_HUMAN (6-290): 6.53e-73: 264: 48.32