HitPredict

Interactor 1: DX39A (O00148)
ATP-dependent RNA helicase DDX39A (EC 3.6.4.13) (DEAD box protein 39) (Nuclear RNA helicase URH49)
Gene: DDX39A

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DEAD~Helicase_C, Helicase_C~Helicase_C, Helicase_C~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016020 - membrane and 1 others more... GO:0016887 - ATP hydrolysis activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 427 Hs			1 1912
+	Hs
		1046035 DX39B_HUMAN (1-427): 1.27e-135: 397: 89.49		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1059774 DDX17_HUMAN (19-422): 2.24e-131: 396: 25.73		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		571456 DDX5_HUMAN (6-420): 8.36e-132: 394: 24.82		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		117127 DX39A_HUMAN (1-427): 1.15e-136: 400: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018469 DX39B_HUMAN (1-427): 1.27e-135: 397: 89.49		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018621 DDX17_HUMAN (19-422): 2.24e-131: 396: 25.73		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		571420 DDX5_HUMAN (6-420): 8.36e-132: 394: 24.82		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		757615 IF4A3_HUMAN (51-417): 5.06e-77: 246: 36.14		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		757587 IF4A3_HUMAN (51-417): 5.06e-77: 246: 36.14		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Zm
		12049 C0PHE3_MAIZE (1-420): 1.29e-126: 373: 35.63		A0A1D6FIP6_MAIZE (596-1632): 0: 770: 27.20