HitPredict

Interactor 1: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Interactor 2: NSD3 (Q9BZ95)
Histone-lysine N-methyltransferase NSD3 (EC 2.1.1.370) (EC 2.1.1.371) (Nuclear SET domain-containing protein 3) (Protein whistle) (WHSC1-like 1 isoform 9 with methyltransferase activity to lysine) (Wolf-Hirschhorn syndrome candidate 1-like protein 1) (WHSC1-like protein 1)
Gene: NSD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SET~fn3, SET~SPRY
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 783 Hs			1 1437
+	Hs
		1282033 TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40		NSD3_HUMAN (1-1437): 0: 1169: 100.00
+	Hs
		1317504 TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57		NSD3_HUMAN (1-1437): 0: 1169: 100.00
+	Hs
		331832 TRI67_HUMAN (1-783): 0: 593: 100.00		NSD2_HUMAN (140-1414): 0: 825: 45.08
+	Hs
		855498 TRI67_HUMAN (1-783): 0: 593: 100.00		MSH6_HUMAN (233-594): 7.56e-72: 266: 18.55
+	Hs
		1171280 TRI67_HUMAN (1-783): 0: 593: 100.00		EHMT2_HUMAN (1029-1281): 2.28e-60: 229: 22.84
+	Hs
		1080055 TRI67_HUMAN (1-783): 0: 593: 100.00		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		975275 TRI67_HUMAN (1-783): 0: 593: 100.00		KMT2A_HUMAN (1131-1285): 7.1e-40: 164: 30.13
+	Hs
		855476 TRI14_HUMAN (301-760): 3.67e-71: 241: 17.80		MSH6_HUMAN (233-594): 7.56e-72: 266: 18.55
+	Hs
		1080208 TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		1080304 TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		1080002 LIN41_HUMAN (192-513): 3.7e-27: 120: 20.43		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		1282073 TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40		KMT2B_HUMAN (1323-1421): 9.58e-09: 62.5: 19.83
+	Hs
		1317542 TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57		KMT2B_HUMAN (1323-1421): 9.58e-09: 62.5: 19.83
+	Hs
		585025 RO52_HUMAN (120-378): 1.33e-12: 72.8: 10.81		EZH1_HUMAN (1076-1270): 4.39e-59: 220: 30.24
+	Hs
		584972 RO52_HUMAN (120-378): 1.33e-12: 72.8: 10.81		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		1080310 TRIM4_HUMAN (1-123): 1.51e-09: 63.2: 18.70		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78
+	Hs
		1052669 TRI25_HUMAN (1-158): 8.85e-09: 60.9: 13.29		EZH2_HUMAN (1076-1270): 1.53e-58: 218: 28.78