HitPredict

Interactor 1: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Interactor 2: MRCKB (Q9Y5S2)
Serine/threonine-protein kinase MRCK beta (EC 2.7.11.1) (CDC42-binding protein kinase beta) (CDC42BP-beta) (DMPK-like beta) (Myotonic dystrophy kinase-related CDC42-binding kinase beta) (MRCK beta) (Myotonic dystrophy protein kinase-like beta)
Gene: CDC42BPB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~fn3
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 783 Hs			1 1711
+	Hs
		1137875 TRI67_HUMAN (1-783): 0: 593: 100.00		MRCKA_HUMAN (1-1710): 0: 1386: 60.78
+	Hs
		148970 TRI67_HUMAN (1-783): 0: 593: 100.00		CTRO_HUMAN (5-1085): 8.52e-127: 442: 24.93
+	Hs
		1170558 TRI67_HUMAN (1-783): 0: 593: 100.00		TAOK1_HUMAN (50-1034): 2.95e-130: 434: 14.43
+	Hs
		296414 TRI67_HUMAN (1-783): 0: 593: 100.00		STK10_HUMAN (43-1015): 1.26e-120: 406: 16.50
+	Hs
		1172335 TRI67_HUMAN (1-783): 0: 593: 100.00		ST38L_HUMAN (1-421): 5.35e-120: 388: 37.93
+	Hs
		1069619 TRI67_HUMAN (1-783): 0: 593: 100.00		STK38_HUMAN (4-421): 5.25e-119: 385: 38.77
+	Hs
		568710 TRI67_HUMAN (1-783): 0: 593: 100.00		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Hs
		610741 TRI67_HUMAN (1-783): 0: 593: 100.00		KAPCB_HUMAN (50-375): 2.2e-119: 382: 35.52
+	Hs
		1172202 TRI67_HUMAN (1-783): 0: 593: 100.00		TNIK_HUMAN (52-833): 5.89e-94: 336: 14.30
+	Hs
		1071653 TRI67_HUMAN (1-783): 0: 593: 100.00		KS6A2_HUMAN (2-389): 6.73e-94: 323: 21.41
+	Hs
		1073440 TRI67_HUMAN (1-783): 0: 593: 100.00		KS6A1_HUMAN (2-354): 1.8e-89: 310: 22.16
+	Hs
		254493 TRI67_HUMAN (1-783): 0: 593: 100.00		ROCK2_HUMAN (362-1073): 2.09e-23: 110: 13.59
+	Hs
		1035181 TRI67_HUMAN (1-783): 0: 593: 100.00		ROCK1_HUMAN (360-1074): 6.44e-17: 89.6: 13.02
+	Hs
		1069648 TRIM6_HUMAN (195-774): 1.16e-86: 284: 12.69		STK38_HUMAN (4-421): 5.25e-119: 385: 38.77
+	Mm
		949339 TRI46_MOUSE (1-769): 7.66e-98: 322: 20.36		TNIK_MOUSE (52-836): 1.02e-93: 335: 13.91
+	Hs
		568758 TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Hs
		568786 TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57		KAPCA_HUMAN (48-375): 1.99e-119: 382: 34.72
+	Hs
		1049033 TRI14_HUMAN (301-760): 3.67e-71: 241: 17.80		STK38_HUMAN (4-421): 5.25e-119: 385: 38.77
+	Hs
		1318737 TRIM2_HUMAN (194-767): 1.51e-82: 280: 15.95		TNIK_HUMAN (52-833): 5.89e-94: 336: 14.30
+	Mm
		949424 TRIM3_MOUSE (190-767): 6.68e-78: 268: 14.85		TNIK_MOUSE (52-836): 1.02e-93: 335: 13.91