HitPredict

Interactor 1: PDLI1 (O00151)
PDZ and LIM domain protein 1 (C-terminal LIM domain protein 1) (Elfin) (LIM domain protein CLP-36)
Gene: PDLIM1

Interactor 2: PE2R4 (P35408)
Prostaglandin E2 receptor EP4 subtype (PGE receptor EP4 subtype) (PGE2 receptor EP4 subtype) (Prostanoid EP4 receptor)
Gene: PTGER4

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.48	0.50	0.494

Property	Details
Experiments	28298427
Identification Methods	two hybrid, ubiquitin reconstruction
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 329 Hs			1 488
+	Hs
		626684 SNTA1_HUMAN (5-258): 2.28e-29: 119: 14.23		ADA1D_HUMAN (14-486): 1.68e-88: 283: 15.06
+	Hs
		626685 SNTB2_HUMAN (6-278): 2.94e-25: 107: 12.72		ADA1D_HUMAN (14-486): 1.68e-88: 283: 15.06
+	Hs
		1029370 SNTA1_HUMAN (5-258): 2.28e-29: 119: 14.23		PD2R_HUMAN (43-373): 1.36e-83: 264: 30.50
+	Mm
		57476 Q3UVD6_MOUSE (4-256): 2.21e-25: 107: 13.16		A2ANQ2_MOUSE (14-485): 1.19e-83: 270: 14.85
+	Hs
		441651 SNTA1_HUMAN (5-258): 2.28e-29: 119: 14.23		ADRB1_HUMAN (1-365): 1.96e-74: 244: 17.90
+	Hs
		658229 SNTA1_HUMAN (5-258): 2.28e-29: 119: 14.23		5HT2C_HUMAN (37-412): 7.46e-70: 231: 15.09
+	Hs
		783792 SNTA1_HUMAN (5-258): 2.28e-29: 119: 14.23		5HT2B_HUMAN (16-387): 8.11e-69: 229: 17.17
+	Hs
		656994 DLG4_HUMAN (1-87): 9.22e-20: 92.2: 25.53		5HT2A_HUMAN (1-395): 6.05e-76: 248: 16.75
+	Hs
		676803 SNTA1_HUMAN (5-258): 2.28e-29: 119: 14.23		SSR1_HUMAN (8-345): 1.9e-66: 220: 15.59
+	Hs
		441650 DLG4_HUMAN (1-87): 9.22e-20: 92.2: 25.53		ADRB1_HUMAN (1-365): 1.96e-74: 244: 17.90
+	Mm
		830267 DLG4_MOUSE (1-87): 1e-19: 91.8: 25.53		SSR4_MOUSE (18-349): 2.62e-71: 233: 16.82
+	Mm
		578603 MAGI3_MOUSE (13-204): 1.38e-11: 67.5: 12.95		ADRB2_MOUSE (13-427): 3.71e-80: 257: 15.18
+	Hs
		658221 DLG4_HUMAN (1-87): 9.22e-20: 92.2: 25.53		5HT2C_HUMAN (37-412): 7.46e-70: 231: 15.09
+	Mm
		676818 DLG4_MOUSE (1-87): 1e-19: 91.8: 25.53		SSR2_MOUSE (19-377): 8.22e-71: 231: 17.27
+	Hs
		600726 DLG4_HUMAN (1-87): 9.22e-20: 92.2: 25.53		DRD1_HUMAN (34-384): 1.78e-69: 230: 17.50
+	Hs
		429068 MAGI3_HUMAN (13-154): 5.58e-12: 68.7: 13.99		ADRB2_HUMAN (13-352): 1.09e-78: 253: 16.47
+	Mm
		676812 DLG4_MOUSE (1-87): 1e-19: 91.8: 25.53		SSR1_MOUSE (10-348): 9.97e-69: 226: 15.54
+	Hs
		441653 MAGI3_HUMAN (13-154): 5.58e-12: 68.7: 13.99		ADRB1_HUMAN (1-365): 1.96e-74: 244: 17.90
+	Hs
		441656 MAGI1_HUMAN (2-267): 7e-12: 68.7: 12.59		ADRB1_HUMAN (1-365): 1.96e-74: 244: 17.90
+	Rn
		574798 MAGI3_RAT (13-71): 1.19e-11: 67.9: 26.67		ADRB1_RAT (34-365): 4.67e-71: 234: 17.07