Interactor 1: RGMC (Q6ZVN8)
Hemojuvelin (Hemochromatosis type 2 protein) (Hemojuvelin BMP coreceptor) (RGM domain family member C)
Gene: HJV

Interactor 2: NEO1 (Q92859)
Neogenin (Immunoglobulin superfamily DCC subclass member 2)
Gene: NEO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.716

The method score is based on:

Property Details
Experiments 18335997
Identification Methods surface plasmon resonance, pull down, static light scattering
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains RGM_C~fn3, RGM_N~fn3
Common GO terms GO:0005886 - plasma membrane
GO:0006879 - intracellular iron ion homeostasis
GO:0009986 - cell surface
GO:0060586 - multicellular organismal-level iron ion homeostasis
GO:0098797 - plasma membrane protein complex
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 426
Hs

1 1461
+ Dr
+ Dr
+ Dr
+ Dr
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024