HitPredict

Interactor 1: PAXI1 (Q6ZW49)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: PAXIP1

Interactor 2: KMT2C (Q8NEZ4)
Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)
Gene: KMT2C

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 0.60 0.662

The method score is based on:

Property Details
Experiments 17925232, 17500065, 24981860
Identification Methods affinity chromatography technology, biochemical, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0035097 - histone methyltransferase complex
GO:0044666 - MLL3/4 complex
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1069
Hs

1 4911
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024