HitPredict

Interactor 1: PAXI1 (Q6ZW49)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: PAXIP1

Interactor 2: FEV (Q99581)
Protein FEV (Fifth Ewing variant protein) (PC12 ETS domain-containing transcription factor 1) (PC12 ETS factor 1) (Pet-1)
Gene: FEV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1069 Hs			1 238
+	Hs
		507457 PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Hs
		542031 PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00		ETS1_HUMAN (8-151): 2.42e-54: 182: 46.31
+	Hs
		840387 PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00		ERF_HUMAN (24-183): 1.94e-46: 163: 41.25
+	Hs
		794550 PAXI1_HUMAN (1-419): 4.99e-91: 316: 100.00		ETV4_HUMAN (36-186): 3.64e-46: 161: 39.74
+	Hs
		1304713 CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07		FEV_HUMAN (1-238): 7.78e-93: 274: 100.00
+	Hs
		507518 CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86
+	Hs
		1243834 KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11		FEV_HUMAN (1-238): 7.78e-93: 274: 100.00
+	Hs
		781237 CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07		ETV3_HUMAN (30-193): 7.5e-48: 166: 39.39
+	Hs
		785417 CHD7_HUMAN (188-893): 7.26e-34: 144: 9.07		ELK3_HUMAN (61-215): 1.5e-41: 147: 29.68
+	Hs
		507468 KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11		ERG_HUMAN (3-237): 5.54e-66: 213: 46.86