HitPredict

Interactor 1: PAXI1 (Q6ZW49)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: PAXIP1

Interactor 2: DPY30 (Q9C005)
Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L)
Gene: DPY30

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.657

Property	Details
Experiments	24981860, 17500065, 17178841
Identification Methods	affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035097 - histone methyltransferase complex GO:0044666 - MLL3/4 complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1069 Hs			1 99
+	Mm
		1157872 PAXI1_MOUSE (592-1069): 2.91e-144: 461: 92.47		DPY30_MOUSE (1-99): 4.11e-50: 155: 97.98
+	Hs
		1056973 MDC1_HUMAN (187-1069): 1.3e-57: 220: 14.77		DPY30_HUMAN (1-99): 2.56e-50: 155: 100.00
+	Hs
		1243840 KMT2C_HUMAN (162-612): 3.03e-12: 73.5: 9.11		DPY30_HUMAN (1-99): 2.56e-50: 155: 100.00