HitPredict

Interactor 1: RFPLB (Q6ZWI9)
Ret finger protein-like 4B (RING finger protein 211)
Gene: RFPL4B

Interactor 2: ZN446 (Q9NWS9)
Zinc finger protein 446 (Zinc finger protein with KRAB and SCAN domains 20)
Gene: ZNF446

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 263 Hs			1 450
+	Hs
		563717 RFPLB_HUMAN (1-263): 1.25e-87: 262: 100.00		ZKSC1_HUMAN (95-421): 2.39e-74: 244: 14.29
+	Hs
		1281575 TRI39_HUMAN (3-99): 7.09e-16: 78.9: 22.68		ZKSC4_HUMAN (11-449): 8.19e-125: 375: 23.51
+	Hs
		537095 TRI27_HUMAN (1-64): 5.49e-14: 73.1: 31.25		ZN446_HUMAN (1-450): 1.58e-114: 345: 100.00
+	Hs
		836602 TRI41_HUMAN (2-39): 3.27e-13: 70.8: 36.84		ZN165_HUMAN (15-448): 6.3e-115: 347: 24.29
+	Hs
		536846 TRI27_HUMAN (1-64): 5.49e-14: 73.1: 31.25		ZNF79_HUMAN (108-450): 7.84e-97: 301: 18.29
+	Hs
		1203436 TRI69_HUMAN (1-90): 7.26e-16: 78.5: 24.44		ZN483_HUMAN (231-449): 1.69e-74: 249: 23.55
+	Hs
		161855 TRI41_HUMAN (2-39): 3.27e-13: 70.8: 36.84		ZN263_HUMAN (123-450): 3.51e-68: 231: 17.88
+	Hs
		64163 TRI39_HUMAN (3-99): 7.09e-16: 78.9: 22.68		ZN726_HUMAN (43-327): 7.79e-64: 218: 7.85
+	Hs
		1261083 TRI41_HUMAN (2-39): 3.27e-13: 70.8: 36.84		ZN251_HUMAN (193-450): 2.85e-51: 185: 20.06
+	Hs
		536720 TRI27_HUMAN (1-64): 5.49e-14: 73.1: 31.25		ZN250_HUMAN (17-299): 1.24e-50: 182: 8.14
+	Hs
		549202 TRI41_HUMAN (2-39): 3.27e-13: 70.8: 36.84		ZN250_HUMAN (17-299): 1.24e-50: 182: 8.14
+	Hs
		1128449 TRI39_HUMAN (3-99): 7.09e-16: 78.9: 22.68		ZN484_HUMAN (59-450): 8.3e-40: 154: 12.29
+	Hs
		1086106 TRI11_HUMAN (1-94): 4.33e-19: 88.1: 21.28		ZSC26_HUMAN (106-450): 4.79e-35: 137: 14.20
+	Hs
		1238810 TRI39_HUMAN (3-99): 7.09e-16: 78.9: 22.68		ZN383_HUMAN (75-329): 2.72e-36: 140: 8.37
+	Hs
		1086100 TRI41_HUMAN (2-39): 3.27e-13: 70.8: 36.84		ZSC26_HUMAN (106-450): 4.79e-35: 137: 14.20
+	Hs
		1261126 TRI41_HUMAN (2-39): 3.27e-13: 70.8: 36.84		ZN629_HUMAN (40-417): 9.72e-30: 124: 10.73
+	Hs
		1158013 TRI69_HUMAN (1-90): 7.26e-16: 78.5: 24.44		Q6P088_HUMAN (21-104): 9.97e-25: 103: 59.52
+	Hs
		1261137 TRI41_HUMAN (2-39): 3.27e-13: 70.8: 36.84		ZSC21_HUMAN (138-300): 3.58e-22: 100: 6.55
+	Hs
		997546 TRI39_HUMAN (3-99): 7.09e-16: 78.9: 22.68		ZN543_HUMAN (41-199): 2.79e-17: 86.2: 7.55
+	Hs
		536912 TRI27_HUMAN (1-64): 5.49e-14: 73.1: 31.25		ZSC29_HUMAN (327-448): 1.22e-12: 72: 38.53