Interactor 1: IF2A (Q6ZWX6)
Eukaryotic translation initiation factor 2 subunit 1 (Eukaryotic translation initiation factor 2 subunit alpha) (eIF-2-alpha) (eIF-2A) (eIF-2alpha) (eIF2-alpha)
Gene: Eif2s1

Interactor 2: E2AK3 (Q9Z2B5)
Eukaryotic translation initiation factor 2-alpha kinase 3 (EC 2.7.11.1) (PRKR-like endoplasmic reticulum kinase) (Pancreatic eIF2-alpha kinase)
Gene: Eif2ak3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 28869608
Identification Methods protein kinase assay
Interaction Type phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~S1
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006412 - translation
GO:0034198 - cellular response to amino acid starvation
GO:0034976 - response to endoplasmic reticulum stress
and 1 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 315
Mm

1 1114
+ Hs
+ Dm
+ Hs
+ Dm
+ Mm
+ Hs
+ Hs
+ Sp
+ Sp
+ Zm
+ Sc
+ Oc
+ Pf

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Last updated: 15 Jul 2024