Interactor 1: TF2H5 (Q6ZYL4)
General transcription factor IIH subunit 5 (General transcription factor IIH polypeptide 5) (TFB5 ortholog) (TFIIH basal transcription factor complex TTD-A subunit) (TFIIH subunit p8)
Gene: GTF2H5

Interactor 2: TF2H4 (Q92759)
General transcription factor IIH subunit 4 (Basic transcription factor 2 52 kDa subunit) (BTF2 p52) (General transcription factor IIH polypeptide 4) (TFIIH basal transcription factor complex p52 subunit)
Gene: GTF2H4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 26496610, 28514442, 24981860, 33961781, 26340423, 32296183, 19172752, unassigned1304
Identification Methods affinity chromatography technology, pull down, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Tfb2~Tfb5, Tfb2_C~Tfb5
Common GO terms GO:0000439 - transcription factor TFIIH core complex
GO:0005654 - nucleoplasm
GO:0005669 - transcription factor TFIID complex
GO:0005675 - transcription factor TFIIH holo complex
GO:0006289 - nucleotide-excision repair
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 71
Hs

1 462
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024