Interactor 1: UBP49 (Q70CQ1)
Ubiquitin carboxyl-terminal hydrolase 49 (EC 3.4.19.12) (Deubiquitinating enzyme 49) (Ubiquitin thioesterase 49) (Ubiquitin-specific-processing protease 49)
Gene: USP49

Interactor 2: UBP44 (Q9H0E7)
Ubiquitin carboxyl-terminal hydrolase 44 (EC 3.4.19.12) (Deubiquitinating enzyme 44) (Ubiquitin thioesterase 44) (Ubiquitin-specific-processing protease 44)
Gene: USP44

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 32076268, 19615732
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~UCH, zf-UBP~zf-UBP
Common GO terms GO:0004843 - cysteine-type deubiquitinase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0008270 - zinc ion binding
GO:0016579 - protein deubiquitination
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 688
Hs

1 712
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024