HitPredict

Interactor 1: RAPH1 (Q70E73)
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein) (Lamellipodin) (Proline-rich EVH1 ligand 2) (PREL-2) (Protein RMO1)
Gene: RAPH1

Interactor 2: SH3K1 (Q96B97)
SH3 domain-containing kinase-binding protein 1 (CD2-binding protein 3) (CD2BP3) (Cbl-interacting protein of 85 kDa) (Human Src family kinase-binding protein 1) (HSB-1)
Gene: SH3KBP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19531213
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~SH3_9
Common GO terms	GO:0005829 - cytosol GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1250 Hs			1 665
+	Hs
		209092 RAPH1_HUMAN (1-1250): 0: 627: 100.00		NCK2_HUMAN (184-428): 2.06e-16: 83.6: 12.77
+	Hs
		924543 GRB10_HUMAN (111-591): 4.23e-121: 389: 24.95		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		1056926 MDC1_HUMAN (718-1249): 2.96e-14: 80.3: 14.37		SH3K1_HUMAN (1-665): 8.63e-127: 391: 100.00
+	Ce
		666202 MIG10_CAEEL (190-655): 8.61e-87: 301: 32.21		SEM5_CAEEL (2-167): 1.56e-29: 118: 21.08
+	Hs
		554292 MUC1_HUMAN (540-1249): 7.9e-36: 150: 11.97		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		924760 PRG4_HUMAN (510-1162): 1.96e-15: 84.1: 12.08		GRB2_HUMAN (2-158): 6.97e-33: 128: 19.91
+	Hs
		257713 ANR17_HUMAN (543-1095): 3.34e-14: 80.2: 12.82		ITSN2_HUMAN (30-455): 2.08e-26: 117: 15.30