HitPredict

Interactor 1: UBP45 (Q70EL2)
Ubiquitin carboxyl-terminal hydrolase 45 (EC 3.4.19.12) (Deubiquitinating enzyme 45) (Ubiquitin thioesterase 45) (Ubiquitin-specific-processing protease 45)
Gene: USP45

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 814 Hs			1 126
+	Hs
		1129817 UBP45_HUMAN (1-814): 0: 621: 100.00		H2B2F_HUMAN (1-126): 1.7e-55: 170: 99.21
+	Hs
		241667 UBP16_HUMAN (15-814): 1.68e-166: 504: 35.97		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		707805 UBP16_HUMAN (15-814): 1.68e-166: 504: 35.97		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918798 UBP16_HUMAN (15-814): 1.68e-166: 504: 35.97		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		1307158 UBP16_HUMAN (15-814): 1.68e-166: 504: 35.97		H2B1L_HUMAN (1-126): 2.43e-53: 165: 97.62
+	Hs
		1087499 UBP20_HUMAN (35-812): 1.97e-116: 376: 18.44		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		1087506 UBP15_HUMAN (170-812): 2.88e-109: 359: 17.49		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		707666 UBP43_HUMAN (178-812): 3.98e-93: 317: 17.92		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		1087489 UBP22_HUMAN (444-814): 1.04e-49: 185: 16.01		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		707665 UBP51_HUMAN (541-812): 6.67e-49: 186: 19.57		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		707794 UBP22_HUMAN (444-814): 1.04e-49: 185: 16.01		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		271037 UBP2_HUMAN (588-811): 1.06e-45: 175: 25.22		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		707807 UBP3_HUMAN (469-810): 8.99e-42: 162: 18.61		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		918801 UBP3_HUMAN (469-810): 8.99e-42: 162: 18.61		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		707745 UBP44_HUMAN (615-812): 4.08e-16: 84.7: 31.50		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		1087213 UBP49_HUMAN (596-812): 1.16e-14: 80.1: 29.68		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		1282957 UBP44_HUMAN (615-812): 4.08e-16: 84.7: 31.50		H2B1A_HUMAN (1-126): 1.15e-47: 151: 84.25
+	Sc
		355943 UBP8_YEAST (668-810): 6.65e-15: 80.1: 34.90		H2B2_YEAST (3-125): 4.15e-41: 134: 71.55
+	Sc
		355547 UBP8_YEAST (668-810): 6.65e-15: 80.1: 34.90		H2B1_YEAST (4-125): 8.17e-37: 123: 72.13