Interactor 1: UBP50 (Q70EL3)
Ubiquitin carboxyl-terminal hydrolase 50 (EC 3.4.19.12) (Ubiquitin-specific peptidase 50)
Gene: USP50

Interactor 2: ASC (Q9ULZ3)
Apoptosis-associated speck-like protein containing a CARD (hASC) (Caspase recruitment domain-containing protein 5) (PYD and CARD domain-containing protein) (Target of methylation-induced silencing 1)
Gene: PYCARD

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.52 0.60 0.561

The method score is based on:

Property Details
Experiments 28094437
Identification Methods affinity chromatography technology, enzymatic study
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0032731 - positive regulation of interleukin-1 beta production
GO:2001056 - positive regulation of cysteine-type endopeptidase activity
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 339
Hs

1 195
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024