HitPredict

Interactor 1: MOB2 (Q70IA6)
MOB kinase activator 2 (HCCA2) (Mob2 homolog) (Mps one binder kinase activator-like 2)
Gene: MOB2

Interactor 2: MOB1A (Q9H8S9)
MOB kinase activator 1A (Mob1 alpha) (Mob1A) (Mob1 homolog 1B) (Mps one binder kinase activator-like 1B)
Gene: MOB1A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	37536630, 24255178
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Mob1_phocein~Mob1_phocein
Common GO terms	GO:0001934 - positive regulation of protein phosphorylation GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0030295 - protein kinase activator activity and 1 others more... GO:0046872 - metal ion binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 237 Hs			1 216
+	Hs
		1185501 MOB1B_HUMAN (1-209): 5.1e-110: 316: 41.32		MOB1A_HUMAN (1-216): 3.44e-119: 339: 100.00
+	Hs
		1174205 MOB1B_HUMAN (1-209): 5.1e-110: 316: 41.32		MOB2_HUMAN (1-213): 2.01e-86: 256: 40.38
+	Sc
		774474 MOB2_YEAST (8-206): 1.72e-83: 252: 34.15		MOB1_YEAST (2-214): 2.22e-86: 259: 49.54
+	Sc
		774471 MOB1_YEAST (11-208): 1.75e-80: 245: 35.58		MOB1_YEAST (2-214): 2.22e-86: 259: 49.54