HitPredict

Interactor 1: MOB3C (Q70IA8)
MOB kinase activator 3C (Mob1 homolog 2C) (Mps one binder kinase activator-like 2C)
Gene: MOB3C

Interactor 2: LATS2 (Q9NRM7)
Serine/threonine-protein kinase LATS2 (EC 2.7.11.1) (Kinase phosphorylated during mitosis protein) (Large tumor suppressor homolog 2) (Serine/threonine-protein kinase kpm) (Warts-like kinase)
Gene: LATS2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	19739119
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 216 Hs			1 1088
+	Hs
		1198336 MOB3B_HUMAN (1-216): 4.23e-116: 331: 71.76		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1285989 MOB3A_HUMAN (5-216): 1.49e-112: 322: 74.06		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1333705 MOB1A_HUMAN (13-214): 2.75e-107: 308: 52.48		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		1185503 MOB1B_HUMAN (13-214): 2.54e-106: 306: 50.50		LATS2_HUMAN (1-1088): 0: 983: 100.00
+	Hs
		325791 MOB3B_HUMAN (1-216): 4.23e-116: 331: 71.76		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325785 MOB3C_HUMAN (1-216): 1.99e-115: 329: 100.00		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325844 MOB3A_HUMAN (5-216): 1.49e-112: 322: 74.06		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325891 MOB1A_HUMAN (13-214): 2.75e-107: 308: 52.48		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		325787 MOB1B_HUMAN (13-214): 2.54e-106: 306: 50.50		LATS1_HUMAN (1-1083): 0: 734: 49.61
+	Hs
		1333714 MOB1A_HUMAN (13-214): 2.75e-107: 308: 52.48		ST38L_HUMAN (592-1051): 1.3e-146: 448: 41.30
+	Hs
		1069652 MOB1A_HUMAN (13-214): 2.75e-107: 308: 52.48		STK38_HUMAN (583-1065): 5.24e-146: 447: 40.58
+	Hs
		1185506 MOB1B_HUMAN (13-214): 2.54e-106: 306: 50.50		ST38L_HUMAN (592-1051): 1.3e-146: 448: 41.30
+	Hs
		1069623 MOB1B_HUMAN (13-214): 2.54e-106: 306: 50.50		STK38_HUMAN (583-1065): 5.24e-146: 447: 40.58
+	Dm
		1099222 MOB1_DROME (13-214): 1.93e-104: 301: 48.02		Q24590_DROME (167-1039): 3.13e-139: 449: 39.64
+	Dm
		1278870 MOB1_DROME (13-214): 1.93e-104: 301: 48.02		WARTS_DROME (167-1039): 7.21e-137: 443: 39.71
+	Dm
		1278869 MOB1_DROME (13-214): 1.93e-104: 301: 48.02		TRC_DROME (577-1049): 1.4e-142: 438: 39.66
+	Hs
		117030 MOB1A_HUMAN (13-214): 2.75e-107: 308: 52.48		SGK1_HUMAN (608-1042): 1.07e-131: 408: 28.51
+	Sc
		774485 MOB1_YEAST (10-214): 2.96e-86: 259: 36.89		CBK1_YEAST (347-1051): 3.83e-143: 450: 29.56
+	Sp
		293187 MOB1_SCHPO (13-214): 5.82e-95: 277: 44.55		SID2_SCHPO (501-1052): 1.07e-137: 430: 27.87
+	Sc
		520615 MOB1_YEAST (10-214): 2.96e-86: 259: 36.89		YPK1_YEAST (343-1057): 5.4e-136: 428: 20.83