HitPredict

Interactor 1: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Interactor 2: CBX8 (Q9HC52)
Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1)
Gene: CBX8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	18927235
Identification Methods	protein complementation assay, bimolecular fluorescence complementation
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 389
+	Hs
		935259 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX8_HUMAN (1-389): 5.01e-104: 314: 100.00
+	Hs
		935387 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CDYL_HUMAN (2-312): 1.24e-66: 223: 14.65
+	Hs
		316000 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX6_HUMAN (1-386): 1.08e-65: 216: 33.26
+	Hs
		316040 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX6_HUMAN (1-386): 1.08e-65: 216: 33.26
+	Hs
		123231 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX4_HUMAN (1-349): 3.84e-62: 210: 21.93
+	Hs
		123254 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX4_HUMAN (1-349): 3.84e-62: 210: 21.93
+	Hs
		935156 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		MPP8_HUMAN (6-356): 2.27e-52: 188: 18.85
+	Hs
		934768 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX2_HUMAN (2-348): 3.75e-46: 167: 22.03
+	Hs
		327837 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX7_HUMAN (1-235): 2.71e-41: 147: 28.46
+	Hs
		327844 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX7_HUMAN (1-235): 2.71e-41: 147: 28.46
+	Hs
		934987 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CDYL2_HUMAN (9-312): 9.92e-33: 130: 12.81
+	Hs
		203659 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV91_HUMAN (11-102): 9.92e-27: 112: 25.25
+	Hs
		935237 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		SUV92_HUMAN (9-103): 2.94e-26: 110: 22.43
+	Hs
		934721 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX3_HUMAN (9-144): 1.3e-26: 106: 25.74
+	Hs
		1027017 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX3_HUMAN (9-144): 1.3e-26: 106: 25.74
+	Hs
		800341 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX5_HUMAN (11-144): 1.06e-25: 104: 25.00
+	Hs
		800397 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX5_HUMAN (11-144): 1.06e-25: 104: 25.00
+	Hs
		934657 H31_HUMAN (1-136): 1.98e-62: 189: 99.27		CBX1_HUMAN (17-122): 3.63e-23: 97.5: 28.97
+	Mm
		935445 H31_MOUSE (1-136): 1.98e-62: 189: 99.27		CBX1_MOUSE (17-122): 3.63e-23: 97.5: 28.97
+	Hs
		949795 H31T_HUMAN (1-136): 8.3e-62: 187: 96.32		CBX1_HUMAN (17-122): 3.63e-23: 97.5: 28.97