HitPredict

Interactor 1: Q71LX8 (Q71LX8)
Heat shock protein HSP 90-beta
Gene: Hsp90ab1

Interactor 2: AGO2 (Q8CJG0)
Protein argonaute-2 (Argonaute2) (mAgo2) (EC 3.1.26.n2) (Argonaute RISC catalytic component 2) (Eukaryotic translation initiation factor 2C 2) (eIF-2C 2) (eIF2C 2) (Piwi/argonaute family protein meIF2C2) (Protein slicer)
Gene: AGO2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	22918229
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003725 - double-stranded RNA binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 724 Mm			1 860
+	Mm
		432448 HS90A_MOUSE (1-724): 0: 1062: 84.72		AGO2_MOUSE (1-860): 0: 1216: 100.00
+	Hs
		438614 HS90B_HUMAN (1-724): 0: 1079: 99.59		AGO2_HUMAN (21-860): 0: 1193: 99.88
+	Hs
		432355 HS90A_HUMAN (1-724): 0: 1066: 85.66		AGO2_HUMAN (21-860): 0: 1193: 99.88
+	Hs
		438615 HS90B_HUMAN (1-724): 0: 1079: 99.59		AGO1_HUMAN (18-860): 0: 1173: 83.16
+	Hs
		432356 HS90A_HUMAN (1-724): 0: 1066: 85.66		AGO1_HUMAN (18-860): 0: 1173: 83.16
+	Hs
		438537 HS90B_HUMAN (1-724): 0: 1079: 99.59		AGO3_HUMAN (17-860): 0: 1155: 80.07
+	Hs
		432271 HS90A_HUMAN (1-724): 0: 1066: 85.66		AGO3_HUMAN (17-860): 0: 1155: 80.07
+	Hs
		438545 HS90B_HUMAN (1-724): 0: 1079: 99.59		AGO4_HUMAN (13-860): 0: 1136: 78.14
+	Hs
		432278 HS90A_HUMAN (1-724): 0: 1066: 85.66		AGO4_HUMAN (13-860): 0: 1136: 78.14
+	Dm
		365460 HSP83_DROME (8-724): 0: 1052: 78.24		Q32KD4_DROME (4-860): 0: 1129: 72.97
+	At
		138329 HS903_ARATH (10-724): 0: 1001: 66.71		AGO1_ARATH (4-859): 0: 1082: 40.93
+	Dm
		1103835 Q9VAY2_DROME (4-692): 0: 845: 46.29		Q32KD4_DROME (4-860): 0: 1129: 72.97
+	Ce
		108540 ENPL1_CAEEL (3-699): 0: 846: 44.07		G5EGR6_CAEEL (20-860): 0: 1095: 67.09
+	Hs
		432159 HS90A_HUMAN (1-724): 0: 1066: 85.66		PIWL1_HUMAN (20-827): 0: 751: 21.74
+	Hs
		432088 HS90A_HUMAN (1-724): 0: 1066: 85.66		PIWL2_HUMAN (3-822): 0: 716: 20.94
+	Dm
		365485 HSP83_DROME (8-724): 0: 1052: 78.24		AGO2_DROME (31-819): 0: 713: 30.84
+	Hs
		432003 HS90A_HUMAN (1-724): 0: 1066: 85.66		PIWL4_HUMAN (20-823): 0: 680: 21.68
+	Dm
		365462 HSP83_DROME (8-724): 0: 1052: 78.24		AGO3_DROME (14-827): 0: 636: 20.67
+	Dm
		365480 HSP83_DROME (8-724): 0: 1052: 78.24		PIWI_DROME (31-811): 0: 579: 22.20
+	Hs
		431946 HS90A_HUMAN (1-724): 0: 1066: 85.66		Q5TA56_HUMAN (27-219): 4.14e-88: 280: 65.84