HitPredict

Interactor 1: LARP4 (Q71RC2)
La-related protein 4 (La ribonucleoprotein domain family member 4)
Gene: LARP4

Interactor 2: IF2B1 (Q9NZI8)
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1)
Gene: IGF2BP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29395067
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	La~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0003730 - mRNA 3'-UTR binding GO:0005829 - cytosol GO:0010494 - cytoplasmic stress granule
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 577
+	Hs
		128251 LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1268185 LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		403355 LA_HUMAN (119-325): 8.13e-45: 167: 15.66		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		128204 LAR1B_HUMAN (67-631): 2.76e-36: 148: 16.40		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		128194 LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22		IF2B3_HUMAN (1-577): 4.61e-149: 443: 71.85
+	Hs
		1116591 LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22		IF2B1_HUMAN (1-577): 4.69e-147: 437: 100.00
+	Hs
		1174882 LARP4_HUMAN (1-724): 9.66e-130: 403: 100.00		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1268210 LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1268144 LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70		FUBP3_HUMAN (190-413): 5.36e-18: 89.3: 18.25
+	Hs
		1072101 LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22		PCBP2_HUMAN (407-575): 6.35e-44: 162: 27.43
+	Hs
		1268138 LAR4B_HUMAN (9-724): 5.72e-59: 214: 32.70		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		403307 LA_HUMAN (119-325): 8.13e-45: 167: 15.66		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		1145724 LAR1B_HUMAN (67-631): 2.76e-36: 148: 16.40		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1116665 LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1162728 LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72		IF2B2_HUMAN (79-477): 2.19e-19: 93.9: 14.84
+	Hs
		1162637 LARP1_HUMAN (98-620): 1.39e-30: 131: 14.72		FUBP1_HUMAN (118-353): 1.13e-15: 82.3: 14.01
+	Hs
		1071891 LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22		PCBP1_HUMAN (476-574): 1.53e-12: 71: 17.17
+	Hs
		884314 LARP7_HUMAN (123-365): 8.03e-34: 139: 17.22		PCBP3_HUMAN (65-270): 1.9e-09: 61.5: 15.31