Interactor 1: MED25 (Q71SY5)
Mediator of RNA polymerase II transcription subunit 25 (Activator interaction domain-containing protein 1) (Activator-recruited cofactor 92 kDa component) (ARC92) (Mediator complex subunit 25) (p78)
Gene: MED25

Interactor 2: MED23 (Q9ULK4)
Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130)
Gene: MED23

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 1.00 0.922

The method score is based on:

Property Details
Experiments 25281560, 33961781, 14657022, 25792360, 24882805
Identification Methods proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med23~Med25_VWA
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex
GO:0016592 - mediator complex
GO:0032968 - positive regulation of transcription elongation by RNA polymerase II
and 3 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 747
Hs

1 1368
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024