HitPredict

Interactor 1: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Interactor 2: CYLD (Q9NQC7)
Ubiquitin carboxyl-terminal hydrolase CYLD (EC 3.4.19.12) (Deubiquitinating enzyme CYLD) (Ubiquitin thioesterase CYLD) (Ubiquitin-specific-processing protease CYLD)
Gene: CYLD

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	18222923, 19893491
Identification Methods	pull down, affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 451 Hs			1 956
+	Hs
		1309507 TBA1C_HUMAN (1-451): 0: 726: 98.00		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		933632 TBA4A_HUMAN (1-450): 0: 717: 96.00		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		1343340 TBA8_HUMAN (1-440): 0: 701: 90.68		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		428455 TBB5_HUMAN (1-439): 0: 695: 40.77		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Hs
		933989 TBB4B_HUMAN (1-437): 0: 693: 40.50		CYLD_HUMAN (1-956): 0: 1872: 100.00
+	Mm
		933729 TBA1A_MOUSE (1-440): 0: 713: 100.00		CYLD_MOUSE (1-956): 0: 1825: 94.46