HitPredict

Interactor 1: H2AV (Q71UI9)
Histone H2A.V (H2A.F/Z) (H2A.Z variant histone 2)
Gene: H2AZ2

Interactor 2: H2B1H (Q93079)
Histone H2B type 1-H (H2B-clustered histone 9) (Histone H2B.j) (H2B/j)
Gene: H2BC9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	1.00	0.839

Property	Details
Experiments	30021884, 34349018, 37071682
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Hs			1 126
+	Hs
		1129818 H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00		H2B2F_HUMAN (1-126): 1.7e-55: 170: 99.21
+	Hs
		469948 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B1O_HUMAN (1-126): 2.36e-55: 170: 99.21
+	Hs
		470046 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B2F_HUMAN (1-126): 1.7e-55: 170: 99.21
+	Hs
		420793 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B1J_HUMAN (1-126): 7.3e-55: 169: 97.62
+	Hs
		420848 H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00		H2B1J_HUMAN (1-126): 7.3e-55: 169: 97.62
+	Hs
		470038 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B2E_HUMAN (1-126): 5.74e-55: 169: 98.41
+	Hs
		470118 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B1H_HUMAN (1-126): 4.31e-55: 169: 100.00
+	Hs
		241424 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		241566 H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00		H2B1K_HUMAN (1-126): 1.18e-54: 168: 98.41
+	Hs
		469955 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B1B_HUMAN (1-126): 1.44e-54: 168: 96.83
+	Hs
		469983 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2BFS_HUMAN (1-126): 1.16e-54: 168: 96.83
+	Hs
		469988 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		883032 H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00		H2BFS_HUMAN (1-126): 1.16e-54: 168: 96.83
+	Hs
		918464 H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00		H2B1C_HUMAN (1-126): 1.07e-54: 168: 99.21
+	Hs
		469984 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B1D_HUMAN (1-126): 3.03e-54: 167: 98.41
+	Hs
		886139 H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00		H2B1D_HUMAN (1-126): 3.03e-54: 167: 98.41
+	Hs
		470139 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B1L_HUMAN (1-126): 2.43e-53: 165: 97.62
+	Hs
		470086 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B3B_HUMAN (1-126): 1.45e-52: 163: 96.03
+	Hs
		1175297 H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00		H2B1A_HUMAN (1-126): 1.15e-47: 151: 84.25
+	Hs
		470121 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		H2B1A_HUMAN (1-126): 1.15e-47: 151: 84.25