HitPredict

Interactor 1: H2AV (Q71UI9)
Histone H2A.V (H2A.F/Z) (H2A.Z variant histone 2)
Gene: H2AZ2

Interactor 2: PMYT1 (Q99640)
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase)
Gene: PKMYT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 128 Hs			1 499
+	Hs
		1305397 H2A1J_HUMAN (5-125): 1.65e-54: 168: 62.30		PMYT1_HUMAN (1-499): 3.82e-135: 401: 100.00
+	Hs
		555439 H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81		STK4_HUMAN (80-385): 1.39e-101: 315: 26.52
+	Hs
		625560 H2A1H_HUMAN (5-125): 4.19e-54: 167: 62.30		CDK2_HUMAN (107-360): 2.87e-100: 305: 27.43
+	Hs
		391553 H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30		CDK2_HUMAN (107-360): 2.87e-100: 305: 27.43
+	Hs
		469953 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		WEE1_HUMAN (100-359): 5.49e-33: 134: 34.59
+	Hs
		469974 H2AZ_HUMAN (1-127): 3.62e-60: 182: 98.43		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		851556 H2AV_HUMAN (1-128): 7.15e-60: 182: 100.00		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		851642 H2A1A_HUMAN (5-125): 2.64e-55: 170: 62.30		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		851513 H2A2C_HUMAN (5-128): 2.15e-54: 168: 62.40		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		851576 H2A2B_HUMAN (5-127): 1.29e-54: 168: 60.48		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		851654 H2A1J_HUMAN (5-125): 1.65e-54: 168: 62.30		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		851664 H2AJ_HUMAN (5-128): 1.33e-54: 168: 60.80		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		851636 H2A1H_HUMAN (5-125): 4.19e-54: 167: 62.30		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		391827 H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30		M4K1_HUMAN (110-362): 2.43e-20: 96.7: 32.21
+	Hs
		391607 H2A1B_HUMAN (5-125): 1.25e-53: 166: 62.30		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		555364 H2AX_HUMAN (5-124): 1.36e-53: 166: 62.81		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		594834 H2A1D_HUMAN (5-125): 9.61e-54: 166: 63.12		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		851543 H2A2A_HUMAN (5-125): 7.47e-54: 166: 63.12		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		851557 H2A3_HUMAN (5-125): 8.16e-54: 166: 63.12		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65
+	Hs
		851622 H2A1C_HUMAN (5-125): 9.3e-54: 166: 62.30		NEK4_HUMAN (113-361): 3.88e-20: 95.9: 30.65