HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1063 Hs			1 173
+	Hs
		117646 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Hs
		117512 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		GAK_HUMAN (9-151): 1.05e-38: 141: 17.42
+	Hs
		260504 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Hs
		214439 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Hs
		260644 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Hs
		297327 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Hs
		214543 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Hs
		64598 MYH7B_HUMAN (8-1045): 0: 1034: 26.67		TENS2_HUMAN (4-168): 8.07e-39: 142: 13.74
+	Hs
		260524 MYH9_HUMAN (5-974): 0: 994: 29.37		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Hs
		260637 MYO5B_HUMAN (46-959): 0: 970: 30.60		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Sp
		1350785 MYO1_SCHPO (29-768): 1.77e-176: 550: 39.89		FLP1_SCHPO (3-160): 6.58e-39: 140: 21.97
+	Hs
		260550 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00