HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005102 - signaling receptor binding GO:0005524 - ATP binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0045121 - membrane raft and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1063 Hs			1 509
+	Hs
		297270 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		LCK_HUMAN (1-509): 0: 661: 100.00
+	Hs
		214469 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		LCK_HUMAN (1-509): 0: 661: 100.00
+	Hs
		411905 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		LCK_HUMAN (1-509): 0: 661: 100.00
+	Hs
		297273 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		LYN_HUMAN (1-509): 0: 582: 62.72
+	Hs
		214472 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		LYN_HUMAN (1-509): 0: 582: 62.72
+	Hs
		523231 MYH4_HUMAN (5-1045): 0: 1032: 26.70		SRC_HUMAN (20-507): 0: 586: 55.00
+	Hs
		412058 MYH9_HUMAN (5-974): 0: 994: 29.37		FYN_HUMAN (30-507): 0: 586: 59.01
+	Hs
		433620 MYH9_HUMAN (5-974): 0: 994: 29.37		LYN_HUMAN (1-509): 0: 582: 62.72
+	Hs
		111443 MYH9_HUMAN (5-974): 0: 994: 29.37		J3QRU1_HUMAN (26-507): 0: 581: 58.06
+	Hs
		433272 MYH9_HUMAN (5-974): 0: 994: 29.37		YES_HUMAN (26-507): 0: 581: 58.06
+	Hs
		724720 MYH9_HUMAN (5-974): 0: 994: 29.37		BLK_HUMAN (1-509): 0: 557: 59.35
+	Hs
		433732 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		LYN_HUMAN (1-509): 0: 582: 62.72