HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: CALM3 (P0DP25)
Calmodulin-3
Gene: CALM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	EF-hand_7~IQ, EF-hand_7~Myosin_head, EF-hand_7~Myosin_TH1
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1063 Hs			1 149
+	Hs
		117566 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		117567 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		CALM2_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		117594 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		CALL3_HUMAN (1-149): 1.98e-53: 167: 84.56
+	Hs
		297277 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		297278 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		CALM2_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		297298 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		CALL3_HUMAN (1-149): 1.98e-53: 167: 84.56
+	Dm
		906666 MY61F_DROME (36-1059): 0: 1062: 51.41		CALM_DROME (1-149): 5.63e-56: 173: 97.99
+	Hs
		214479 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		214480 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		484046 MYO1A_HUMAN (46-1059): 0: 1053: 42.11		CALM2_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		111438 J3QRN6_HUMAN (45-1008): 0: 1044: 40.73		CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Dm
		906697 MYO7A_DROME (34-945): 0: 995: 32.97		CALM_DROME (1-149): 5.63e-56: 173: 97.99
+	Hs
		648467 MYH9_HUMAN (5-974): 0: 994: 29.37		CALL3_HUMAN (1-149): 1.98e-53: 167: 84.56
+	Hs
		484218 MYO5B_HUMAN (46-959): 0: 970: 30.60		CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Sc
		420270 MYO3_YEAST (43-779): 0: 573: 41.49		CALM_YEAST (1-75): 2.74e-14: 67.4: 40.79
+	Sc
		420336 MYO5_YEAST (41-752): 0: 570: 41.82		CALM_YEAST (1-75): 2.74e-14: 67.4: 40.79
+	Sp
		409421 MYO1_SCHPO (29-768): 1.77e-176: 550: 39.89		CALM_SCHPO (73-149): 6.82e-15: 69.1: 40.26
+	Hs
		483923 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		CALM1_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		483998 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		CALM2_HUMAN (1-149): 1.99e-56: 174: 100.00
+	Hs
		484116 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		CALM3_HUMAN (1-149): 1.99e-56: 174: 100.00