HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: CFTR (P13569)
Cystic fibrosis transmembrane conductance regulator (CFTR) (ATP-binding cassette sub-family C member 7) (Channel conductance-controlling ATPase) (EC 5.6.1.6) (cAMP-dependent chloride channel)
Gene: CFTR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	26618866, 29924966
Identification Methods	affinity chromatography technology, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 1063 Hs			1 1480
+	Hs
		297284 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		522586 MYH7_HUMAN (4-1060): 0: 1068: 27.29		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		214487 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529841 MYO1A_HUMAN (46-1059): 0: 1053: 42.11		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528357 MYH6_HUMAN (4-1060): 0: 1050: 26.70		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529959 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529895 MYH2_HUMAN (5-1045): 0: 1045: 26.83		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		502902 MYH3_HUMAN (5-1045): 0: 1044: 26.86		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528400 MYH8_HUMAN (5-1047): 0: 1039: 26.26		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		522533 MYH1_HUMAN (5-1045): 0: 1037: 26.33		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		64579 MYH7B_HUMAN (8-1045): 0: 1034: 26.67		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529972 MYH4_HUMAN (5-1045): 0: 1032: 26.70		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		69508 MYO1G_HUMAN (42-1055): 0: 1021: 38.54		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		528675 MYH9_HUMAN (5-974): 0: 994: 29.37		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529903 MYO5B_HUMAN (46-959): 0: 970: 30.60		CFTR_HUMAN (1-1480): 0: 1031: 100.00
+	Hs
		529052 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		CFTR_HUMAN (1-1480): 0: 1031: 100.00