HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: TMOD1 (P28289)
Tropomodulin-1 (Erythrocyte tropomodulin) (E-Tmod)
Gene: TMOD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	26496610, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007015 - actin filament organization GO:0016020 - membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1063 Hs			1 359
+	Hs
		117842 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14
+	Hs
		117845 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		TMOD2_HUMAN (1-345): 1.55e-144: 414: 59.25
+	Hs
		214510 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		TMOD1_HUMAN (1-359): 2.27e-161: 457: 100.00
+	Hs
		297421 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14
+	Hs
		297422 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		TMOD2_HUMAN (1-345): 1.55e-144: 414: 59.25
+	Hs
		1348581 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14
+	Hs
		1349403 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		TMOD4_HUMAN (2-343): 3.86e-142: 408: 58.77
+	Hs
		657463 MYH9_HUMAN (5-974): 0: 994: 29.37		TMOD1_HUMAN (1-359): 2.27e-161: 457: 100.00
+	Hs
		657561 MYO5B_HUMAN (46-959): 0: 970: 30.60		TMOD1_HUMAN (1-359): 2.27e-161: 457: 100.00
+	Hs
		725044 MYH9_HUMAN (5-974): 0: 994: 29.37		TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14
+	Hs
		1348577 MYO5B_HUMAN (46-959): 0: 970: 30.60		TMOD3_HUMAN (1-345): 6.33e-150: 428: 62.14
+	Hs
		117894 MYO1F_HUMAN (859-986): 2.17e-10: 67: 31.08		NAL12_HUMAN (185-323): 4.52e-17: 84.8: 19.86