HitPredict

Interactor 1: SEM6D (Q76KF0)
Semaphorin-6D
Gene: Sema6d

Interactor 2: PLXC1 (Q9QZC2)
Plexin-C1 (Virus-encoded semaphorin protein receptor) (CD antigen CD232)
Gene: Plxnc1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	26633812
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PSI~TIG, PSI~Sema, Sema~TIG
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 1073 Mm			1 1574
+	Mm
		936300 SEM6D_MOUSE (1-1073): 0: 1425: 100.00		PLXA1_MOUSE (23-948): 9.24e-111: 391: 16.23
+	Mm
		936315 SEM6D_MOUSE (1-1073): 0: 1425: 100.00		PLXA3_MOUSE (19-925): 1.98e-108: 384: 15.79
+	Mm
		936310 SEM6D_MOUSE (1-1073): 0: 1425: 100.00		PLXA2_MOUSE (20-650): 5.55e-102: 364: 18.32
+	Mm
		1176226 SEM6D_MOUSE (1-1073): 0: 1425: 100.00		PLXA4_MOUSE (39-896): 1.03e-101: 363: 16.14
+	Mm
		192794 SEM6A_MOUSE (17-1067): 0: 1107: 45.20		PLXA1_MOUSE (23-948): 9.24e-111: 391: 16.23
+	Mm
		192795 SEM6A_MOUSE (17-1067): 0: 1107: 45.20		PLXA2_MOUSE (20-650): 5.55e-102: 364: 18.32
+	Mm
		192797 SEM6A_MOUSE (17-1067): 0: 1107: 45.20		PLXA4_MOUSE (39-896): 1.03e-101: 363: 16.14
+	Mm
		139662 SEM3A_MOUSE (1-622): 0: 657: 30.60		SEM3A_MOUSE (18-595): 1.92e-138: 448: 13.79
+	Hs
		1055532 SEM3A_HUMAN (1-627): 0: 663: 31.03		SEM3C_HUMAN (12-596): 7.67e-130: 424: 12.35
+	Hs
		1030135 SEM3C_HUMAN (1-625): 0: 613: 28.04		SEM3F_HUMAN (9-596): 1.47e-135: 441: 13.49
+	Hs
		303598 SEM3D_HUMAN (2-627): 0: 627: 31.17		SEM3C_HUMAN (12-596): 7.67e-130: 424: 12.35
+	Mm
		1112528 SEM3D_MOUSE (2-628): 0: 641: 31.74		PLXD1_MOUSE (7-941): 2.08e-112: 396: 19.33
+	Mm
		936364 SEM3E_MOUSE (13-628): 0: 626: 28.48		PLXD1_MOUSE (7-941): 2.08e-112: 396: 19.33
+	Mm
		139669 SEM3A_MOUSE (1-622): 0: 657: 30.60		PLXA4_MOUSE (39-896): 1.03e-101: 363: 16.14
+	Mm
		936311 SEM3D_MOUSE (2-628): 0: 641: 31.74		PLXA2_MOUSE (20-650): 5.55e-102: 364: 18.32
+	Hs
		165342 SEM3E_HUMAN (13-628): 0: 623: 29.26		PLXD1_HUMAN (7-941): 1.64e-107: 381: 19.33
+	Dm
		218214 O44253_DROME (7-765): 0: 606: 29.13		O96681_DROME (29-877): 2.68e-108: 384: 17.28
+	Dm
		1001985 Q7KK54_DROME (7-765): 0: 604: 29.13		Q0KIF1_DROME (371-877): 1.26e-44: 179: 17.25