HitPredict

Interactor 1: ASXL2 (Q76L83)
Putative Polycomb group protein ASXL2 (Additional sex combs-like protein 2)
Gene: ASXL2

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1435 Hs			1 522
+	Mm
		1141408 ASPP1_MOUSE (140-909): 2.96e-54: 209: 13.08		TRAF3_MOUSE (20-501): 4.18e-85: 275: 22.40
+	Hs
		301782 ZO1_HUMAN (94-797): 1.1e-29: 131: 11.81		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		990867 ZO1_HUMAN (94-797): 1.1e-29: 131: 11.81		TRI68_HUMAN (60-385): 1.41e-42: 160: 12.91
+	Hs
		1023768 ASPP1_HUMAN (508-1019): 2.74e-09: 64.1: 9.34		TRAF1_HUMAN (50-501): 5.58e-64: 216: 19.40
+	Hs
		152568 KMT2D_HUMAN (412-1023): 4.42e-14: 80: 13.50		TRI37_HUMAN (56-501): 7.36e-43: 165: 13.89
+	Hs
		537122 MAGL2_HUMAN (124-1017): 3.2e-14: 80.5: 8.66		TRI27_HUMAN (57-404): 7.01e-43: 161: 12.90
+	Hs
		990906 ZO1_HUMAN (94-797): 1.1e-29: 131: 11.81		RN166_HUMAN (61-222): 7.37e-16: 79.1: 22.94
+	Hs
		1252404 ASPP1_HUMAN (508-1019): 2.74e-09: 64.1: 9.34		LNX1_HUMAN (58-183): 2.59e-11: 68.3: 19.84