HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007015 - actin filament organization GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1063 Hs			1 196
+	Hs
		117577 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		117661 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		117647 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		117501 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		297334 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		214490 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		297290 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120225 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		564757 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120732 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		724757 MYH9_HUMAN (5-974): 0: 994: 29.37		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		724776 MYH9_HUMAN (5-974): 0: 994: 29.37		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		925728 MYO5B_HUMAN (46-959): 0: 970: 30.60		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		900425 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		915640 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		545347 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436279 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		892342 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		893949 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564501 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74