HitPredict

Interactor 1: MYO1C (O00159)
Unconventional myosin-Ic (Myosin I beta) (MMI-beta) (MMIb)
Gene: MYO1C

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005938 - cell cortex GO:0016604 - nuclear body and 1 others more... GO:0031267 - small GTPase binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 1063 Hs			1 914
+	Hs
		297411 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		214669 MYO1B_HUMAN (46-1058): 0: 1058: 39.77		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1333778 MYO1A_HUMAN (46-1059): 0: 1053: 42.11		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725023 MYH9_HUMAN (5-974): 0: 994: 29.37		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1333804 MYO5B_HUMAN (46-959): 0: 970: 30.60		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		50534 MYO1C_HUMAN (1-1063): 0: 1215: 100.00		PKHG3_HUMAN (394-892): 2.49e-76: 273: 18.53
+	Hs
		50539 MYO1D_HUMAN (45-1056): 0: 1076: 39.87		PKHG3_HUMAN (394-892): 2.49e-76: 273: 18.53
+	Hs
		724913 MYH9_HUMAN (5-974): 0: 994: 29.37		ARG28_HUMAN (216-807): 7.17e-88: 309: 12.32
+	Hs
		50564 MYH9_HUMAN (5-974): 0: 994: 29.37		PKHG3_HUMAN (394-892): 2.49e-76: 273: 18.53
+	Hs
		724971 MYH9_HUMAN (5-974): 0: 994: 29.37		ARHGH_HUMAN (398-726): 8.05e-68: 249: 23.82
+	Hs
		167121 MYO5A_HUMAN (11-1020): 0: 1049: 28.73		ARHGB_HUMAN (453-651): 2.54e-12: 73.2: 23.53
+	Hs
		1021706 MYO1E_HUMAN (859-986): 1.78e-10: 67.4: 31.76		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		117915 MYO1F_HUMAN (859-986): 2.17e-10: 67: 31.08		ECT2_HUMAN (1-914): 0: 886: 100.00