HitPredict

Interactor 1: MOB4 (Q7K0E3)
MOB kinase activator-like 4 (Mob as tumor suppressor protein 4) (Dmob4) (Mps one binder kinase activator-like 4)
Gene: MOB4

Interactor 2: HIPPO (Q8T0S6)
Serine/threonine-protein kinase hippo (EC 2.7.11.1) (Drosophila homolog of MST1 and MST2) (STE20-like kinase MST) (dMST)
Gene: hpo

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20797625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 223 Dm			1 669
+	Dm
		1249830 MOB1_DROME (19-222): 8.71e-91: 267: 18.87		HIPPO_DROME (1-669): 0: 542: 100.00
+	Dm
		1178607 MOB4_DROME (1-223): 1.17e-107: 310: 100.00		Q9VEN3_DROME (37-379): 2.01e-118: 369: 40.11
+	Hs
		1377585 PHOCN_HUMAN (1-223): 1.24e-107: 310: 80.00		STK24_HUMAN (33-316): 5.77e-120: 366: 51.39
+	Hs
		131625 PHOCN_HUMAN (1-223): 1.24e-107: 310: 80.00		STK25_HUMAN (26-392): 9.65e-118: 360: 41.24
+	Hs
		1350187 PHOCN_HUMAN (1-223): 1.24e-107: 310: 80.00		STK26_HUMAN (32-406): 1.7e-117: 359: 40.10
+	Hs
		1350192 S4R3N1_HUMAN (14-223): 2.13e-100: 293: 80.19		STK26_HUMAN (32-406): 1.7e-117: 359: 40.10
+	Hs
		1026924 MOB3C_HUMAN (19-213): 1.23e-88: 262: 19.21		PAK2_HUMAN (26-317): 5.83e-118: 364: 37.08
+	Hs
		1233571 PHOCN_HUMAN (1-223): 1.24e-107: 310: 80.00		MINK1_HUMAN (33-320): 1.38e-62: 228: 42.05
+	Hs
		1356420 PHOCN_HUMAN (1-223): 1.24e-107: 310: 80.00		TNIK_HUMAN (33-320): 1.39e-62: 228: 41.06
+	Mm
		949324 PHOCN_MOUSE (1-223): 1.24e-107: 310: 80.00		TNIK_MOUSE (33-320): 1.02e-62: 228: 41.06
+	Dm
		56110 MOB1_DROME (19-222): 8.71e-91: 267: 18.87		A1ZBH7_DROME (29-308): 1.36e-67: 242: 43.90
+	Hs
		1198329 MOB3B_HUMAN (20-213): 2e-92: 271: 20.79		MINK1_HUMAN (33-320): 1.38e-62: 228: 42.05
+	Hs
		1174260 MOB3C_HUMAN (19-213): 1.23e-88: 262: 19.21		MINK1_HUMAN (33-320): 1.38e-62: 228: 42.05
+	Hs
		1023145 PHOCN_HUMAN (1-223): 1.24e-107: 310: 80.00		STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60
+	Hs
		1027459 PHOCN_HUMAN (1-223): 1.24e-107: 310: 80.00		STK3_HUMAN (502-661): 1.12e-16: 85.2: 24.22
+	Hs
		1023070 MOB1B_HUMAN (19-221): 1.2e-91: 269: 18.48		STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60
+	Hs
		1023117 MOB1A_HUMAN (17-221): 1.1e-91: 269: 18.31		STK4_HUMAN (537-661): 8.11e-18: 88.9: 29.60
+	Hs
		1027394 MOB3B_HUMAN (20-213): 2e-92: 271: 20.79		STK3_HUMAN (502-661): 1.12e-16: 85.2: 24.22
+	Hs
		1027391 MOB1B_HUMAN (19-221): 1.2e-91: 269: 18.48		STK3_HUMAN (502-661): 1.12e-16: 85.2: 24.22
+	Hs
		1027437 MOB1A_HUMAN (17-221): 1.1e-91: 269: 18.31		STK3_HUMAN (502-661): 1.12e-16: 85.2: 24.22