HitPredict

Interactor 1: Q7K148 (Q7K148)
Proteasome subunit beta
Gene: Prosbeta5

Interactor 2: Q9V3P3 (Q9V3P3)
LD45860p (Proteasome regulator dREG) (Proteasome regulator gamma, isoform A) (Proteasome regulator gamma, isoform B)
Gene: REG

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	22036573, 25294943
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PA28_beta~Proteasome
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 282 Dm			1 245
+	Hs
		656058 PSB8_HUMAN (1-277): 9.51e-104: 305: 48.74		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		656084 PSB8_HUMAN (1-277): 9.51e-104: 305: 48.74		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77
+	Dm
		1278635 PSA5_DROME (41-273): 2.51e-87: 262: 17.55		Q9V3P3_DROME (1-245): 5.84e-117: 335: 100.00
+	Hs
		656192 PSA5_HUMAN (41-272): 1.3e-88: 265: 18.60		PSME3_HUMAN (7-245): 3.59e-112: 323: 48.76
+	Hs
		156268 PSA7_HUMAN (46-269): 2.53e-85: 257: 15.95		PSME3_HUMAN (7-245): 3.59e-112: 323: 48.76
+	Hs
		638103 PSA4_HUMAN (43-269): 9.16e-85: 256: 17.30		PSME3_HUMAN (7-245): 3.59e-112: 323: 48.76
+	Dm
		1358994 Q9W470_DROME (47-267): 2.25e-78: 241: 28.51		Q9V3P3_DROME (1-245): 5.84e-117: 335: 100.00
+	Dm
		1358986 Q9VUJ1_DROME (47-267): 1.41e-75: 233: 27.60		Q9V3P3_DROME (1-245): 5.84e-117: 335: 100.00
+	Hs
		656704 PSB5_HUMAN (1-273): 8.79e-89: 266: 52.38		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		656208 PSA5_HUMAN (41-272): 1.3e-88: 265: 18.60		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		656335 PSA5_HUMAN (41-272): 1.3e-88: 265: 18.60		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77
+	Hs
		899007 PSB7_HUMAN (39-265): 6.52e-77: 236: 28.63		PSME3_HUMAN (7-245): 3.59e-112: 323: 48.76
+	Hs
		156276 PSA7_HUMAN (46-269): 2.53e-85: 257: 15.95		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		638116 PSA4_HUMAN (43-269): 9.16e-85: 256: 17.30		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		156373 PSA7_HUMAN (46-269): 2.53e-85: 257: 15.95		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77
+	Hs
		638215 PSA4_HUMAN (43-269): 9.16e-85: 256: 17.30		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77
+	Hs
		771451 PSB10_HUMAN (47-256): 3.95e-83: 252: 29.05		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		771479 PSB10_HUMAN (47-256): 3.95e-83: 252: 29.05		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77
+	Hs
		986839 PSB7_HUMAN (39-265): 6.52e-77: 236: 28.63		PSME1_HUMAN (8-245): 2.69e-102: 298: 37.40
+	Hs
		1303494 PSB7_HUMAN (39-265): 6.52e-77: 236: 28.63		PSME2_HUMAN (8-245): 1.14e-100: 294: 32.77