HitPredict

Interactor 1: ADRM1 (Q7K2G1)
Proteasomal ubiquitin receptor ADRM1 homolog (Regulatory particle non-ATPase 13 protein) (p42E)
Gene: Rpn13

Interactor 2: PSMD1 (Q9V3P6)
26S proteasome non-ATPase regulatory subunit 1 (26S proteasome regulatory complex subunit p110) (26S proteasome regulatory subunit RPN2)
Gene: Rpn2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	14605208, 22036573
Identification Methods	two hybrid, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000502 - proteasome complex GO:0005634 - nucleus GO:0005838 - proteasome regulatory particle GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 389 Dm			1 1020
+	Hs
		1081035 ADRM1_HUMAN (12-361): 5.72e-130: 380: 38.34		PSMD1_HUMAN (3-1001): 0: 1176: 60.30
+	Sp
		251854 RP13A_SCHPO (16-347): 9.41e-84: 258: 22.69		RPN2_SCHPO (3-1017): 0: 1018: 42.27
+	Ce
		998365 ADRM1_CAEEL (1-378): 4.67e-98: 298: 30.89		PSMD1_CAEEL (4-1016): 0: 933: 32.82
+	Hs
		1027664 ADRM1_HUMAN (12-361): 5.72e-130: 380: 38.34		PSMD2_HUMAN (9-812): 0: 757: 16.90
+	Dm
		1179241 ADRM1_DROME (1-389): 8.1e-156: 446: 100.00		Q9VW54_DROME (13-812): 0: 617: 17.03
+	Sp
		953214 RP13B_SCHPO (1-349): 5.11e-107: 321: 24.93		RPN1_SCHPO (9-810): 0: 574: 16.86
+	Sp
		953221 RP13A_SCHPO (16-347): 9.41e-84: 258: 22.69		RPN1_SCHPO (9-810): 0: 574: 16.86