HitPredict

Interactor 1: Q7K2L1 (Q7K2L1)
Origin recognition complex subunit 3
Gene: Orc3

Interactor 2: ORC6 (Q9Y1B2)
Origin recognition complex subunit 6
Gene: ORC6

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.926

Property	Details
Experiments	24137536, 27016737, 29899147, 25762138, 32848132
Identification Methods	affinity chromatography technology, pull down, x-ray crystallography, cross-linking study
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	ORC6~ORC_WH_C
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005664 - nuclear origin of replication recognition complex GO:0006260 - DNA replication GO:0006270 - DNA replication initiation
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 721 Dm			1 257
+	Hs
		1353962 ORC3_HUMAN (4-721): 0: 721: 32.27		ORC6_HUMAN (2-241): 3.24e-98: 288: 27.82
+	At
		1150654 ORC3_ARATH (19-721): 0: 606: 21.57		ORC6_ARATH (5-233): 3.57e-92: 275: 22.58