HitPredict

Interactor 1: Q7K306 (Q7K306)
Cyclin-dependent kinase 4, isoform A (EC 2.7.11.22) (Cyclin-dependent kinase 4, isoform B) (Cyclin-dependent kinase 4, isoform C) (Cyclin-dependent kinase 4, isoform D) (Cyclin-dependent kinase 4, isoform E) (LD31205p)
Gene: Cdk4

Interactor 2: Q7KUZ5 (Q7KUZ5)
Cyclin D, isoform D (Cyclin D, isoform E) (Cyclin D, isoform F (EC 2.7.1.-))
Gene: CycD

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.829

The method score is based on:

Property Details
Experiments 10970847, 12586062, 14605208
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0010821 - regulation of mitochondrion organization
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 317
Dm

1 477
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Last updated: 15 Jul 2024