Interactor 1: IMD (Q7K4Z4)
Protein immune deficiency
Gene: IMD

Interactor 2: CASP8 (Q8IRY7)
Caspase-8 (EC 3.4.22.61) (Death-related ced-3/NEDD2-like protein) [Cleaved into: Caspase-8 subunit p15; Caspase-8 subunit p10]
Gene: Dredd

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.58 0.55 0.569

The method score is based on:

Property Details
Experiments 24891502, 23749869
Identification Methods enzymatic study, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002230 - positive regulation of defense response to virus by host
GO:0005829 - cytosol
GO:0006955 - immune response
GO:0006963 - positive regulation of antibacterial peptide biosynthetic process
GO:0006964 - positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria
and 4 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024