HitPredict

Interactor 1: Q7KA43 (Q7KA43)
Anaphase-promoting complex subunit 11
Gene: lmgA

Interactor 2: Q9I7L8 (Q9I7L8)
Cell division cycle 23, isoform A (Cell division cycle 23, isoform B) (LD09850p)
Gene: Cdc23

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22491092
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0016567 - protein ubiquitination GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0045842 - positive regulation of mitotic metaphase/anaphase transition GO:0051301 - cell division
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 85 Dm			1 678
+	Sc
		561133 APC11_YEAST (1-82): 2.72e-30: 106: 40.00		CDC23_YEAST (10-542): 7.23e-62: 219: 26.54
+	Hs
		1023005 APC11_HUMAN (1-82): 1.6e-28: 99.4: 73.17		CDC16_HUMAN (15-617): 1.4e-61: 218: 15.74
+	Sc
		454932 APC11_YEAST (1-82): 2.72e-30: 106: 40.00		CDC16_YEAST (51-596): 4e-57: 209: 15.63
+	At
		1341344 APC11_ARATH (1-82): 1.47e-30: 104: 60.98		CDC23_ARATH (150-628): 6.1e-24: 108: 13.22
+	Sc
		743233 APC11_YEAST (1-82): 2.72e-30: 106: 40.00		CDC27_YEAST (352-546): 1.19e-12: 73.4: 13.07
+	Hs
		672906 APC11_HUMAN (1-82): 1.6e-28: 99.4: 73.17		CDC27_HUMAN (26-281): 6.33e-14: 77.3: 14.40
+	Xl
		1129161 Q5M7C0_XENLA (1-82): 6.11e-29: 100: 71.95		Q6GQ04_XENLA (402-657): 8.03e-11: 67.6: 14.89
+	Hs
		1284740 RBX2_HUMAN (3-80): 7.44e-22: 83.2: 36.25		TTC28_HUMAN (362-625): 6.57e-16: 84.2: 9.85
+	Hs
		1348493 APC11_HUMAN (1-82): 1.6e-28: 99.4: 73.17		CDC23_HUMAN (254-617): 2.52e-10: 65.7: 11.75
+	Sp
		784815 APC11_SCHPO (1-80): 2.52e-27: 96.7: 49.38		CUT9_SCHPO (176-630): 7.62e-11: 67.3: 10.90