Interactor 1: Q7KJ08 (Q7KJ08)
Anaplastic lymphoma kinase, isoform A (EC 2.7.10.1) (Anaplastic lymphoma kinase, isoform B) (Receptor protein tyrosine kinase ALK splice variant A)
Gene: Alk

Interactor 2: Q7KNQ9 (Q7KNQ9)
Connector enhancer of KSR protein CNK (Connector enhancer of ksr, isoform A) (Connector enhancer of ksr, isoform B) (SD09985p)
Gene: cnk

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.621

The method score is based on:

Property Details
Experiments 29066538
Identification Methods two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains PH~PK_Tyr_Ser-Thr, PK_Tyr_Ser-Thr~SAM_1
Common GO terms GO:0007169 - cell surface receptor protein tyrosine kinase signaling pathway
GO:0070374 - positive regulation of ERK1 and ERK2 cascade
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1701
Dm

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Last updated: 15 Jul 2024